SB 1.5 - The infallible purpose of everything
Learned circles have positively concluded that the infallible purpose (avicyuta arthaḥ) of the advancement of knowledge (buddhi), namely austerities (tapasaḥ), study of the Vedas (śrutasya), sacrifice (sviṣṭasya), chanting of hymns (sūktasya) and charity culminates in the transcendental descriptions of the Lord, who is defined in choice poetry. The results of austerity and other acts are achieved by bhakti. Everything that can be achieved by karma, tapa, jñāna, dāna etc is easily achieved by bhakti. So all the other dharmas are unnecessary. By culture of knowledge the human society can attain perfection of life, which culminates in the realization of the Supreme Being, Viṣṇu. But persons enamored by illusion do not understand this, and they use advancement of knowledge for sense enjoyment. Nārada had already explained that everything in the universe is an emanation from the Lord. They come to be out of His energy, rest on His energy, and after annihilation merge into Him. Nothing is, therefore, different from Him, but at the same time the Lord is always different from them.
All sages and devotees of the Lord have recommended that the subject matter of art, science, philosophy, physics, chemistry, psychology and all other branches of knowledge should be wholly and solely applied in the service of the Lord. The writers, poets and celebrated litterateurs can describe the pastimes of the Lord, just like Vālmīki and Vyāsadeva did. The purport of all scriptural statements is the Supreme Lord. Philosophy and science should be engaged to establish the glory of the Lord. Knowledge not engaged in the service of the Lord is nescience. Scientific knowledge engaged in the service of the Lord and all similar activities are all hari-kīrtana, or glorification of the Lord. Nārada states that the gradual method Vyāsa has delineated is unsatisfactory because it encourages the readers’ tendency to seek self centered pleasure. Pious deeds cannot break their attraction to mundane enjoyment. Although people were meant to understand that all Vedic teachings culminate in devotion to Kṛṣṇa, few people would understand that and would instead chase a mixed perfection thru karma and jñāna.